Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 939496Generated: November 1, 2026

Water → 1-(6-Chloro-2-methylpyridin-3-yl)-2,2,2-trifluoroethanol

https://huagongshe.com/reaction/939496

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantTetrabutylammoniumHCID 16028—
ReactantFluoride IonHCID 28179—
Reactant(Trifluoromethyl)trimethylsilaneHCID 552549—
Reactant6-Chloro-2-methylpyridine-3-carbaldehydeHCID 44754867—
Product1-(6-Chloro-2-methylpyridin-3-yl)-2,2,2-trifluoroethanolHCID 59525938—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-5e6289af70144c14ade1ad2e86d94553
Source noteValidation data from https://doi.org/10.1039/C8SC04228D