2-Bromo-4-methylanisole → 5-chloro-3-hydroxy-3-(2-methoxy-5-methylphenyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

HRID 939528Notes

Reaction equation

HRID 939528 reaction equation
[Br:1][c:2]1[c:3]([O:9][CH3:10])[cH:4][cH:5][c:6]([CH3:8])[cH:7]1.[Cl:11][c:12]1[cH:13][c:14]2[c:15]([n:16][cH:17]1)[NH:18][C:19](=[O:22])[C:20]2=[O:21]>>[c:2]1([C:20]2([OH:21])[c:14]3[cH:13][c:12]([Cl:11])[cH:17][n:16][c:15]3[NH:18][C:19]2=[O:22])[c:3]([O:9][CH3:10])[cH:4][cH:5][c:6]([CH3:8])[cH:7]1

Participants

3

Reactant 2

HCID 891432-Bromo-4-methylanisoleHCID 674305355-chloro-1H-pyrrolo[2,3-b]pyridine-2,3-dione

Product 1

HCID 674301815-chloro-3-hydroxy-3-(2-methoxy-5-methylphenyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one

Sources & evidence

ORD record
ord-05562e832f0b42e097d04770b3a9c713
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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