Ethanol → 3-Ethyl-1-iodo-8-[2-(4-trifluoromethyl-phenyl)-ethyl]-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine
Reaction equation
[CH2:1]([CH3:2])[c:3]1[n:4]([CH2:9][CH2:10][NH2:11])[cH:5][c:6]([I:8])[n:7]1.[CH3:26][CH2:27][OH:28].[F:12][C:13]([c:14]1[cH:15][cH:16][c:17]([CH2:20][CH2:21][CH:22]=[O:23])[cH:18][cH:19]1)([F:24])[F:25]>>[CH2:1]([CH3:2])[c:3]1[n:4]2[c:5]([c:6]([I:8])[n:7]1)[CH:22]([CH2:21][CH2:20][c:17]1[cH:16][cH:15][c:14]([C:13]([F:12])([F:24])[F:25])[cH:19][cH:18]1)[NH:11][CH2:10][CH2:9]2Participants
4
Sources & evidence
- ORD record
- ord-4da5c4bc0b2b4dde9bd77e9d726f3817
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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