Acetic Acid → 1-(3-Fluoropyridin-2-yl)piperidin-4-one
Reaction equation
[CH3:19][C:20](=[O:21])[OH:22].[F:1][c:2]1[c:3]([N:8]2[CH2:9][CH2:10][C:11]3([CH2:12][O:13][O:14][CH2:15]3)[CH2:16][CH2:17]2)[n:4][cH:5][cH:6][cH:7]1.[OH2:18]>>[F:1][c:2]1[c:3]([N:8]2[CH2:9][CH2:10][C:11](=[O:18])[CH2:16][CH2:17]2)[n:4][cH:5][cH:6][cH:7]1Participants
4
Sources & evidence
- ORD record
- ord-0a84ec43871f45b28aaf4c662778f98b
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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