3-(2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-YL)phenyl)pyridine → 5-(4-Fluoro-3-pyridin-3-ylphenyl)-2-trifluoromethyl[1,8]naphthyridine
Reaction equation
[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[n:7][c:8]2[n:9][cH:10][cH:11]1.[F:16][c:17]1[c:18](-[c:32]2[cH:33][n:34][cH:35][cH:36][cH:37]2)[cH:19][c:20]([B:23]2[O:24][C:25]([CH3:26])([CH3:27])[C:28]([CH3:29])([CH3:30])[O:31]2)[cH:21][cH:22]1>>[c:2]1(-[c:20]2[cH:19][c:18](-[c:32]3[cH:33][n:34][cH:35][cH:36][cH:37]3)[c:17]([F:16])[cH:22][cH:21]2)[c:3]2[cH:4][cH:5][c:6]([C:12]([F:13])([F:14])[F:15])[n:7][c:8]2[n:9][cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-557c0a5e1d074e6fb7af4016d4a9b7bf
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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