Methanesulfonyl chloride → [6-Chloro-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-(4-methanesulfonyl-piperazin-1-yl)-methanone
Reaction equation
[CH3:29][S:30]([Cl:31])(=[O:32])=[O:33].[Cl:1][c:2]1[c:3]([O:19][CH:20]2[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]2)[cH:4][c:5]2[cH:6][c:7]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[nH:8][c:9]2[cH:10]1>>[Cl:1][c:2]1[c:3]([O:19][CH:20]2[CH2:21][CH2:22][N:23]([CH:26]([CH3:27])[CH3:28])[CH2:24][CH2:25]2)[cH:4][c:5]2[cH:6][c:7]([C:11](=[O:12])[N:13]3[CH2:14][CH2:15][N:16]([S:30]([CH3:29])(=[O:32])=[O:33])[CH2:17][CH2:18]3)[nH:8][c:9]2[cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-8dcfc34ed4294bc7973e6b59edb37c4a
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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