1-(7-iodo-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-1-yl)-2-phenylethanone → 2-Phenyl-1-{7-[4-(4-(pyrrolidin-1-yl)piperidine-1-carbonyl)phenyl]-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-1-yl}-ethanone
Reaction equation
[I:1][c:2]1[cH:3][c:4]2[c:5]([n:19][cH:20]1)[NH:6][CH2:7][CH2:8][N:9]2[C:10]([CH2:11][c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)=[O:18].[N:21]1([CH:26]2[CH2:27][CH2:28][N:29]([C:32](=[O:33])[c:34]3[cH:35][cH:36][c:37]([B:40]4[O:41][C:42]([CH3:43])([CH3:44])[C:45]([CH3:46])([CH3:47])[O:48]4)[cH:38][cH:39]3)[CH2:30][CH2:31]2)[CH2:22][CH2:23][CH2:24][CH2:25]1>>[c:2]1(-[c:37]2[cH:36][cH:35][c:34]([C:32]([N:29]3[CH2:28][CH2:27][CH:26]([N:21]4[CH2:22][CH2:23][CH2:24][CH2:25]4)[CH2:31][CH2:30]3)=[O:33])[cH:39][cH:38]2)[cH:3][c:4]2[c:5]([n:19][cH:20]1)[NH:6][CH2:7][CH2:8][N:9]2[C:10]([CH2:11][c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)=[O:18]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-626a5b62766644229d3bcd84aae7b20f
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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