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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 940098Generated: October 31, 2026

1-(Thien-2-ylcarbonyl)piperazine → 6-Fluoro-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazine-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrile

https://huagongshe.com/reaction/940098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Thien-2-ylcarbonyl)piperazineHCID 797562—
Reactant4-Chloro-6-fluoro-2-oxo-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrileHCID 69217171—
Product6-Fluoro-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazine-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrileHCID 69216216—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-933690f7449d415c9356469d7d910b5a
Source noteValidation data from https://doi.org/10.1039/C8SC04228D