Dichloromethane → 3-(4-(2-Bromoethyl)phenyl)-5-(5-phenyl-4-propylisoxazol-3-yl)-1,2,4-oxadiazole

HRID 940111Notes

Reaction equation

[Cl:33][CH2:34][Cl:35].[P:29]([Br:30])([Br:31])[Br:32].[c:1]1(-[c:7]2[c:8]([CH2:26][CH2:27][CH3:28])[c:9](-[c:12]3[n:13][c:14](-[c:17]4[cH:18][cH:19][c:20]([CH2:23][CH2:24][OH:25])[cH:21][cH:22]4)[n:15][o:16]3)[n:10][o:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[c:8]([CH2:26][CH2:27][CH3:28])[c:9](-[c:12]3[n:13][c:14](-[c:17]4[cH:18][cH:19][c:20]([CH2:23][CH2:24][Br:30])[cH:21][cH:22]4)[n:15][o:16]3)[n:10][o:11]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 24614Phosphorus tribromide

HCID 583740912-(4-(5-(5-Phenyl-4-propylisoxazol-3-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethanol

Product 1

HCID 583741553-(4-(2-Bromoethyl)phenyl)-5-(5-phenyl-4-propylisoxazol-3-yl)-1,2,4-oxadiazole

Sources & evidence

ORD record: ord-3bd61d7b313c49139c7fc9f3d0ff043c
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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