N-(2-Cyanophenyl)piperazine → 2-[4-([1,3]Thiazolo[5,4-b]pyridin-2-ylmethyl)-1-piperazinyl]benzonitrile
Reaction equation
[Cl:1][CH2:2][c:3]1[s:4][c:5]2[n:6][cH:7][cH:8][cH:9][c:10]2[n:11]1.[N:12]1([c:18]2[c:19]([C:20]#[N:21])[cH:22][cH:23][cH:24][cH:25]2)[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1>>[CH2:2]([c:3]1[s:4][c:5]2[n:6][cH:7][cH:8][cH:9][c:10]2[n:11]1)[N:15]1[CH2:14][CH2:13][N:12]([c:18]2[c:19]([C:20]#[N:21])[cH:22][cH:23][cH:24][cH:25]2)[CH2:17][CH2:16]1Participants
3
Sources & evidence
- ORD record
- ord-ff8c8d02806041f2bc3518266c4dbb99
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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