Methanol → 6-Bromo-4-chloro-1H-pyrrolo[2,3-B]pyridine

HRID 940261Notes

Reaction equation

HRID 940261 reaction equation
[Br:1][c:2]1[cH:3][c:4]([Cl:19])[c:5]2[c:6]([n:7]1)[n:8]([C:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)=[O:18])[cH:9][cH:10]2.[CH3:22][OH:23].[Na+:21].[OH-:20]>>[Br:1][c:2]1[cH:3][c:4]([Cl:19])[c:5]2[c:6]([n:7]1)[nH:8][cH:9][cH:10]2

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 73014178(6-Bromo-4-chloro-pyrrolo[2,3-b]pyridin-1-yl)-phenyl-methanone

Product 1

HCID 247295876-Bromo-4-chloro-1H-pyrrolo[2,3-B]pyridine

Sources & evidence

ORD record
ord-98190307c90143a78d79cfbfb6c862ca
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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