1,4-Dioxaspiro[4.5]decan-8-one → N-(1-(4-oxocyclohexyl)azetidin-3-yl)-2-((6-(trifluoromethyl)quinazolin-4-yl)amino)acetamide
Reaction equation
[NH:12]1[CH2:13][CH:14]([NH:16][C:17]([CH2:18][NH:19][c:20]2[n:21][cH:22][n:23][c:24]3[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][c:29]23)=[O:34])[CH2:15]1.[O:1]1[CH2:4][CH2:3][O:2][C:5]12[CH2:6][CH2:7][C:8](=[O:11])[CH2:9][CH2:10]2>>[CH:5]1([N:12]2[CH2:13][CH:14]([NH:16][C:17]([CH2:18][NH:19][c:20]3[n:21][cH:22][n:23][c:24]4[cH:25][cH:26][c:27]([C:30]([F:31])([F:32])[F:33])[cH:28][c:29]34)=[O:34])[CH2:15]2)[CH2:6][CH2:7][C:8](=[O:11])[CH2:9][CH2:10]1Participants
3
Sources & evidence
- ORD record
- ord-112c2fe4a98144109e1dd54ac14a0a35
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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