Ethanol → 4-Bromo-2-fluoroanisole

HRID 940327Notes

Reaction equation

HRID 940327 reaction equation
[CH3:12][I:13].[CH3:14][CH2:15][OH:16].[F:1][c:2]1[c:3]([OH:9])[cH:4][cH:5][c:6]([Br:8])[cH:7]1.[K+:11].[OH-:10]>>[F:1][c:2]1[c:3]([O:9][CH3:12])[cH:4][cH:5][c:6]([Br:8])[cH:7]1

Participants

6

Reactant 5

HCID 702EthanolHCID 813Potassium CationHCID 961HydroxideHCID 6328Methyl iodideHCID 27249814-Bromo-2-fluorophenol

Product 1

HCID 753784-Bromo-2-fluoroanisole

Sources & evidence

ORD record
ord-f48408832f52450fba324d6bb5b50cd3
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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