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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 940351Generated: October 31, 2026

Tetrahydrofuran → [2-Oxo4-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-butyl]-phosphonic acid dimethyl ester

https://huagongshe.com/reaction/940351

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantDimethyl methylphosphonateHCID 12958—
ReactantEthyl 3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-YL)propanoateHCID 23581268—
ReactantButyllithiumHCID 178418339—
Product[2-Oxo4-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-butyl]-phosphonic acid dimethyl esterHCID 22082659—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-a7def744cb8149159585604162727255
Source noteValidation data from https://doi.org/10.1039/C8SC04228D