Tecastemizole → 1-(3,4,5-trimethoxybenzyl)-3-(3-(4-(1-(4-fluorobenzyl)-1H-benzimidazol-2-yl-amino)piperidin-1-yl)propyl)-3-(4-fluorophenylmethyl)-2-oxopyrrolidine
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:28])[C:9]([CH2:12][CH2:13][CH2:14][O:15][S:16]([CH3:17])(=[O:18])=[O:19])([CH2:20][c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[CH2:10][CH2:11]2)[cH:29][c:30]([O:34][CH3:35])[c:31]1[O:32][CH3:33].[F:36][c:37]1[cH:38][cH:39][c:40]([CH2:41][n:42]2[c:43]([NH:51][CH:52]3[CH2:53][CH2:54][NH:55][CH2:56][CH2:57]3)[n:44][c:45]3[c:46]2[cH:47][cH:48][cH:49][cH:50]3)[cH:58][cH:59]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:28])[C:9]([CH2:12][CH2:13][CH2:14][N:55]3[CH2:54][CH2:53][CH:52]([NH:51][c:43]4[n:42]([CH2:41][c:40]5[cH:39][cH:38][c:37]([F:36])[cH:59][cH:58]5)[c:46]5[c:45]([n:44]4)[cH:50][cH:49][cH:48][cH:47]5)[CH2:57][CH2:56]3)([CH2:20][c:21]3[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]3)[CH2:10][CH2:11]2)[cH:29][c:30]([O:34][CH3:35])[c:31]1[O:32][CH3:33]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7cff80deac6d43439d14d6517b34bdda
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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