Methanol → 1,3-Dibenzyl-4-hydroxypiperidine
Reaction equation
[BH4-:1].[CH2:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[N:10]1[CH2:11][CH:12]([CH2:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[C:13](=[O:16])[CH2:14][CH2:15]1.[CH3:24][OH:25].[Na+:2]>>[CH2:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[N:10]1[CH2:11][CH:12]([CH2:17][c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[CH:13]([OH:16])[CH2:14][CH2:15]1Participants
5
Sources & evidence
- ORD record
- ord-6d2bb62fdcf74554bbc9be2fe2d39b9d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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