5-Bromo-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one → 1'-[(1-Benzyl-2-methyl-1H-indol-3-yl)carbonyl]-5-bromo-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([cH:15][cH:16]1)[C:6]1([O:7][C:8]2=[O:9])[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]1.[CH2:17]([c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1)[n:24]1[c:25]([CH3:36])[c:26]([C:33](=[O:34])[OH:35])[c:27]2[cH:28][cH:29][cH:30][cH:31][c:32]12>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([cH:15][cH:16]1)[C:6]1([O:7][C:8]2=[O:9])[CH2:10][CH2:11][N:12]([C:33]([c:26]2[c:25]([CH3:36])[n:24]([CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[c:32]3[c:27]2[cH:28][cH:29][cH:30][cH:31]3)=[O:34])[CH2:13][CH2:14]1Participants
3
Sources & evidence
- ORD record
- ord-a4255029e1ab44f3ac3c444b38ce76ac
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…