1-(3-Hydroxyphenyl)piperazine → 1-[(5-Acetyl-2-methoxy-6-methylpyridin-3-yl)aminocarbonyl]-4-(3-hydroxyphenyl)piperazine
Reaction equation
[C:1]([CH3:2])(=[O:3])[c:4]1[cH:5][c:6]([NH:13][C:14]([O:15][c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)=[O:22])[c:7]([O:11][CH3:12])[n:8][c:9]1[CH3:10].[OH:23][c:24]1[cH:25][c:26]([N:30]2[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]2)[cH:27][cH:28][cH:29]1>>[C:1]([CH3:2])(=[O:3])[c:4]1[cH:5][c:6]([NH:13][C:14](=[O:22])[N:33]2[CH2:32][CH2:31][N:30]([c:26]3[cH:25][c:24]([OH:23])[cH:29][cH:28][cH:27]3)[CH2:35][CH2:34]2)[c:7]([O:11][CH3:12])[n:8][c:9]1[CH3:10]Participants
3
Sources & evidence
- ORD record
- ord-e53191c1e9ac4d48882768dd087ee5c0
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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