2-Bromomethyl-2,3-dihydro-2,4,6,7-tetramethyl-5-benzofuranamine → 2-[[4-[(9-Fluorenyl)oxy]-1-piperidinyl]methyl]-2,3-dihydro-2,4,6,7-tetramethyl-5-benzofuranamine
Reaction equation
[Br:1][CH2:2][C:3]1([CH3:16])[O:4][c:5]2[c:6]([c:8]([CH3:15])[c:9]([NH2:14])[c:10]([CH3:13])[c:11]2[CH3:12])[CH2:7]1.[cH:17]1[cH:18][cH:19][cH:20][c:21]2[c:29]1[CH:28]([O:30][CH:31]1[CH2:32][CH2:33][NH:34][CH2:35][CH2:36]1)[c:27]1[c:22]-2[cH:23][cH:24][cH:25][cH:26]1>>[CH2:2]([C:3]1([CH3:16])[O:4][c:5]2[c:6]([c:8]([CH3:15])[c:9]([NH2:14])[c:10]([CH3:13])[c:11]2[CH3:12])[CH2:7]1)[N:34]1[CH2:33][CH2:32][CH:31]([O:30][CH:28]2[c:27]3[c:22]([cH:23][cH:24][cH:25][cH:26]3)-[c:21]3[cH:20][cH:19][cH:18][cH:17][c:29]32)[CH2:36][CH2:35]1Participants
3
Sources & evidence
- ORD record
- ord-3ab4d4e1e6fd42a796a2f5f09d6ee9c9
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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