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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 94076Generated: October 25, 2026

Acetic Acid → 3-hydroxy-6-methyl-2-(2,2,2-trifluoro-1-hydroxy-ethyl)-1H-pyridin-4-one

https://huagongshe.com/reaction/94076

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantCarbon DioxideHCID 280—
ReactantHydrochloric AcidHCID 313—
ReactantPotassium CationHCID 813—
ReactantWaterHCID 962—
Reactant2,2,2-Trifluoro-1-methoxyethanolHCID 9892—
ReactantCarbonate IonHCID 19660—
Reactant5-hydroxy-2-methylpyridin-4(1H)-oneHCID 642649—
Product3-hydroxy-6-methyl-2-(2,2,2-trifluoro-1-hydroxy-ethyl)-1H-pyridin-4-oneHCID 25018652—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-5b6336358c81480a8e361724db48f62a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)