2-(Dimethylamino)ethanol → N-(4-chloro-3-(1-(2-(dimethylamino)ethyl)-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide

HRID 940783Notes

Reaction equation

HRID 940783 reaction equation
[CH3:31][N:32]([CH3:33])[CH2:34][CH2:35][OH:36].[Cl:1][c:2]1[c:3](-[c:26]2[n:27][nH:28][cH:29][n:30]2)[c:4]([NH:7][C:8]([CH2:9][n:10]2[c:11](=[O:24])[cH:12][cH:13][c:14]3[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][c:19]23)=[O:25])[s:5][cH:6]1>>[Cl:1][c:2]1[c:3](-[c:26]2[n:27][n:28]([CH2:35][CH2:34][N:32]([CH3:31])[CH3:33])[cH:29][n:30]2)[c:4]([NH:7][C:8]([CH2:9][n:10]2[c:11](=[O:24])[cH:12][cH:13][c:14]3[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][c:19]23)=[O:25])[s:5][cH:6]1

Participants

3

Reactant 2

HCID 79022-(Dimethylamino)ethanolHCID 178521249HCID 178521249, compound

Product 1

HCID 46869288N-(4-chloro-3-(1-(2-(dimethylamino)ethyl)-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide

Sources & evidence

ORD record
ord-e6650110168c466ea03cb6a34251caf7
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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