5-Amino-1-cyclohexyl-5-ethylbarbituric acid → 1-Cyclohexyl-5-ethyl-5-(4,5,6,7-tetrafluoro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione
Reaction equation
[CH2:19]([N:20]1[C:21](=[O:22])[C:23]([CH3:24])([N:25]2[C:29](=[O:42])[c:30]3[c:31]([F:41])[c:32]([F:40])[c:33]([F:39])[c:34]([F:38])[c:35]3[C:36]2=[O:37])[C:26](=[O:27])[NH:28][C:43]1=[O:44])[CH3:45].[NH2:1][C:2]1([CH2:17][CH3:18])[C:3](=[O:16])[NH:4][C:5](=[O:15])[N:6]([CH:9]2[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]2)[C:7]1=[O:8]>>[N:1]1([C:2]2([CH2:17][CH3:18])[C:3](=[O:16])[NH:4][C:5](=[O:15])[N:6]([CH:9]3[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]3)[C:7]2=[O:8])[C:29](=[O:42])[c:30]2[c:31]([F:41])[c:32]([F:40])[c:33]([F:39])[c:34]([F:38])[c:35]2[C:36]1=[O:37]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-22a859ab8df948118b00d43b932ce13c
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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