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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 940848Generated: October 30, 2026

Acetic Acid → Tert-butyl 4-(3-ethoxy-3-oxoprop-1-YN-1-YL)-4-hydroxypiperidine-1-carboxylate

https://huagongshe.com/reaction/940848

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl propiolateHCID 12182—
Reactanttert-Butyl 4-oxopiperidine-1-carboxylateHCID 735900—
ReactantButyllithiumHCID 178418339—
ProductTert-butyl 4-(3-ethoxy-3-oxoprop-1-YN-1-YL)-4-hydroxypiperidine-1-carboxylateHCID 21955240—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-d0515f9c3cba4009bde0216a44f33bc2
Source noteValidation data from https://doi.org/10.1039/C8SC04228D