Methanol → 5,6-Dimethoxy-3-phenyl-3,4-dihydronaphthalen-1(2H)-one

HRID 940866Notes

Reaction equation

HRID 940866 reaction equation
[CH3:1][O:2][c:3]1[c:4]([CH2:11][CH:12]([CH2:13][C:14]([O:16][CH2:15][CH3:17])=[O:18])[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:5][cH:6][cH:7][c:8]1[O:9][CH3:10].[CH3:27][OH:28].[Na+:26].[OH-:25]>>[CH3:1][O:2][c:3]1[c:4]2[c:5]([cH:6][cH:7][c:8]1[O:9][CH3:10])[C:14](=[O:16])[CH2:13][CH:12]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[CH2:11]2

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 19961164Ethyl 4-(2',3'-dimethoxyphenyl)-3-phenylbutyrate

Product 1

HCID 124785445,6-Dimethoxy-3-phenyl-3,4-dihydronaphthalen-1(2H)-one

Sources & evidence

ORD record
ord-6866b841e5854ecd9aa1f9a50f51cc23
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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