6-Iodopyridine-3-carboxylic acid → Ethyl6-iodonicotinoate

HRID 941078Notes

Reaction equation

HRID 941078 reaction equation
[CH2:23]([C:24]([CH2:25][CH3:26])([CH2:27][CH3:28])[C:29]([O-:30])([O-:31])[O-:32])[CH3:33].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1.[I:13][c:14]1[cH:15][cH:16][c:17]([C:18]([OH:19])=[O:20])[cH:21][n:22]1>>[c:2]1([I:13])[n:3][cH:4][c:5]([C:6](=[O:7])[O:8][CH2:9][CH3:10])[cH:11][cH:12]1

Participants

4

Reactant 3

HCID 8190626-Iodopyridine-3-carboxylic acidHCID 2799611Ethyl 6-chloronicotinateHCID 21875354Triethylorthoaceate

Product 1

HCID 10891136Ethyl6-iodonicotinoate

Sources & evidence

ORD record
ord-95fbf33d34ee4870985ff7f728581599
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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