2-Fluoro-4-nitrophenol → 1-(1-Ethyl-4-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-2-yl)-N,N-dimethylmethanamine

HRID 941135Notes

Reaction equation

HRID 941135 reaction equation
[CH2:33]([n:34]1[cH:35][c:36](-[c:37]2[s:38][c:39]3[c:40]([n:41][cH:42][cH:43][c:44]3[O:45][c:46]3[cH:47][cH:48][c:49]([N+:50]([O-:51])=[O:52])[cH:53][c:54]3[F:55])[cH:56]2)[n:57][cH:58]1)[CH3:59].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9](-[c:11]1[n:12][c:13]([CH2:18][N:19]([CH3:20])[CH3:21])[n:14]([CH2:16][CH3:17])[cH:15]1)[s:10]2.[F:22][c:23]1[c:24]([OH:32])[cH:25][cH:26][c:27]([N+:29](=[O:30])[O-:31])[cH:28]1>>[c:2]1([O:32][c:24]2[c:23]([F:22])[cH:28][c:27]([N+:29](=[O:30])[O-:31])[cH:26][cH:25]2)[c:3]2[c:4]([n:5][cH:6][cH:7]1)[cH:8][c:9](-[c:11]1[n:12][c:13]([CH2:18][N:19]([CH3:20])[CH3:21])[n:14]([CH2:16][CH3:17])[cH:15]1)[s:10]2

Participants

4

Reactant 3

HCID 98252-Fluoro-4-nitrophenolHCID 587902451-(4-(7-Chlorothieno[3,2-b]pyridin-2-yl)-1-ethyl-1H-imidazol-2-yl)-N,N-dimethylmethanamineHCID 666490322-(1-Ethyl-1H-imidazol-4-yl)-7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridine

Product 1

HCID 587904001-(1-Ethyl-4-(7-(2-fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-2-yl)-N,N-dimethylmethanamine

Sources & evidence

ORD record
ord-6d6033928f924af2880bcd45d52074ae
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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