Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 941141Generated: October 31, 2026

Toluene → 5-ethyl-5-hydroxy-9-methoxy-4,5-dihydrooxepino[3,4-c]pyridin-3(1H)-one

https://huagongshe.com/reaction/941141

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTert-butyl 3-hydroxy-3-[3-(hydroxymethyl)-2-methoxy-4-pyridinyl]pentanoateHCID 21891952—
Product5-ethyl-5-hydroxy-9-methoxy-4,5-dihydrooxepino[3,4-c]pyridin-3(1H)-oneHCID 10561844—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-86ae334a094046d5aca655ea543f9ff2
Source noteValidation data from https://doi.org/10.1039/C8SC04228D