Ammonia → 6-[1-(4-chlorophenyl)-1H-pyrazol-5-yl]-5-methyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazine-2-carboxamide
Reaction equation
[CH3:35][OH:36].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][cH:11][c:12]2-[c:13]2[c:14]([CH3:34])[n:15](-[c:24]3[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]3)[c:16](=[O:23])[c:17]([C:19]([O:21][CH3:20])=[O:22])[n:18]2)[cH:6][cH:7]1.[NH3:37]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][cH:11][c:12]2-[c:13]2[c:14]([CH3:34])[n:15](-[c:24]3[cH:25][c:26]([C:30]([F:31])([F:32])[F:33])[cH:27][cH:28][cH:29]3)[c:16](=[O:23])[c:17]([C:19](=[O:21])[NH2:37])[n:18]2)[cH:6][cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-ef4cee2be4204a72bd68fc2772ef680d
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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