Acetate → 4-(2-(4-Nitrophenoxy)phenyl)pyrimidin-2-amine

HRID 941202Notes

Reaction equation

HRID 941202 reaction equation
[CH3:2][C:3](=[O:4])[O-:5].[CH3:6][C:7]1([CH3:8])[C:9]([CH3:10])([CH3:11])[O:12][B:13]([c:14]2[c:15]([O:20][c:21]3[cH:22][cH:23][c:24]([N+:27](=[O:28])[O-:29])[cH:25][cH:26]3)[cH:16][cH:17][cH:18][cH:19]2)[O:30]1.[Cl:31][c:32]1[n:33][c:34]([NH2:38])[n:35][cH:36][cH:37]1.[Cl:39][CH2:40][Cl:41].[K+:1].[OH2:42]>>[c:14]1(-[c:32]2[n:33][c:34]([NH2:38])[n:35][cH:36][cH:37]2)[c:15]([O:20][c:21]2[cH:22][cH:23][c:24]([N+:27](=[O:28])[O-:29])[cH:25][cH:26]2)[cH:16][cH:17][cH:18][cH:19]1

Participants

7

Reactant 6

HCID 175AcetateHCID 813Potassium CationHCID 962WaterHCID 6344DichloromethaneHCID 2233322-Amino-4-chloropyrimidineHCID 667316814,4,5,5-Tetramethyl-2-(2-(4-nitrophenoxy)phenyl)-1,3,2-dioxaborolane

Product 1

HCID 667316394-(2-(4-Nitrophenoxy)phenyl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-26693a3c0d124bdaa5e64551916f0d06
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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