HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 941230Generated: October 31, 2026
Hydrochloric Acid → 3-(4-{[2-(4-Chloro-phenyl)-4-(2,2-dimethoxy-ethyl)-thiazole-5-carbonyl]-amino}-2-methoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester
https://huagongshe.com/reaction/941230
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Tert-butyl 3-(4-amino-2-methoxyphenoxy)azetidine-1-carboxylate | HCID 46835556 | — |
| Reactant | 2-(4-Chloro-phenyl)-4-(2,2-dimethoxy-ethyl)-thiazole-5-carboxylic acid | HCID 67460529 | — |
| Product | 3-(4-{[2-(4-Chloro-phenyl)-4-(2,2-dimethoxy-ethyl)-thiazole-5-carbonyl]-amino}-2-methoxy-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester | HCID 67461234 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Validation data from https://doi.org/10.1039/C8SC04228D |
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| ORD ID | ord-da5c10b35c1547a2b9b3fd43f7a2403e |
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| Source note | Validation data from https://doi.org/10.1039/C8SC04228D |
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