Methanol → Methyl 3-amino-2-fluorobenzoate

HRID 941492Notes

Reaction equation

HRID 941492 reaction equation
[CH3:16][OH:17].[NH2:1][c:2]1[c:3]([F:11])[c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][cH:10]1.[S:12]([Cl:13])([Cl:14])=[O:15]>>[NH2:1][c:2]1[c:3]([F:11])[c:4]([C:5]([O:6][CH3:16])=[O:7])[cH:8][cH:9][cH:10]1

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 230943433-Amino-2-fluorobenzoic acid

Product 1

HCID 46311080Methyl 3-amino-2-fluorobenzoate

Sources & evidence

ORD record
ord-74084edb9ad74f1f920d6e055805647c
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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