Cyclobutanesulfonyl chloride → N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)cyclobutanesulfonamide

HRID 941576Notes

Reaction equation

HRID 941576 reaction equation
[CH:1]1([S:5](=[O:6])(=[O:7])[Cl:8])[CH2:2][CH2:3][CH2:4]1.[F:9][c:10]1[cH:11][c:12]([O:27][CH3:28])[c:13]([NH2:26])[c:14]([NH:17][c:18]2[c:19]([F:25])[cH:20][c:21]([I:24])[cH:22][cH:23]2)[c:15]1[F:16]>>[CH:1]1([S:5](=[O:6])(=[O:7])[NH:26][c:13]2[c:12]([O:27][CH3:28])[cH:11][c:10]([F:9])[c:15]([F:16])[c:14]2[NH:17][c:18]2[c:19]([F:25])[cH:20][c:21]([I:24])[cH:22][cH:23]2)[CH2:2][CH2:3][CH2:4]1

Participants

3

Reactant 2

HCID 22636930Cyclobutanesulfonyl chlorideHCID 532609665,6-difluoro-N1-(2-fluoro-4-iodophenyl)-3-methoxybenzene-1,2-diamine

Product 1

HCID 53492296N-(3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-6-methoxyphenyl)cyclobutanesulfonamide

Sources & evidence

ORD record
ord-b2f647bfdc21474a87176e4abd715050
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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