4-(4-Bromobenzyl)morpholine → 1-[4-(Morpholin-4-ylmethyl)phenyl]-3-(piperidin-1-ylmethyl)cyclobutan-1-ol
Reaction equation
[Br:13][c:14]1[cH:15][cH:16][c:17]([CH2:18][N:19]2[CH2:20][CH2:21][O:22][CH2:23][CH2:24]2)[cH:25][cH:26]1.[N:1]1([CH2:7][CH:8]2[CH2:9][C:10](=[O:12])[CH2:11]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1>>[N:1]1([CH2:7][CH:8]2[CH2:9][C:10]([OH:12])([c:14]3[cH:15][cH:16][c:17]([CH2:18][N:19]4[CH2:20][CH2:21][O:22][CH2:23][CH2:24]4)[cH:25][cH:26]3)[CH2:11]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-0dd0deb596af413a8c83164224dacc27
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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