2-Bromo-5-fluoropyridine → N-(4-chloro-3-(5-fluoropyridin-2-yl)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide
Reaction equation
[Cl:1][c:2]1[c:3]([B:22]2[O:23][C:24]([CH3:25])([CH3:26])[C:27]([CH3:28])([CH3:29])[O:30]2)[cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([CH3:20])[n:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)=[O:21])[cH:6][cH:7]1.[F:31][c:32]1[cH:33][cH:34][c:35]([Br:38])[n:36][cH:37]1>>[Cl:1][c:2]1[c:3](-[c:35]2[cH:34][cH:33][c:32]([F:31])[cH:37][n:36]2)[cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([CH3:20])[n:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)=[O:21])[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-44bd0cbd0ddd4e11a900cb8fd5cf26ea
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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