1-Methyl-4-piperidinemethanol → 4-Chloro-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazoline
Reaction equation
[CH3:15][N:16]1[CH2:17][CH2:18][CH:19]([CH2:22][OH:23])[CH2:20][CH2:21]1.[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([OH:14])[c:9]([O:12][CH3:13])[cH:10][c:11]12>>[Cl:1][c:2]1[n:3][cH:4][n:5][c:6]2[cH:7][c:8]([O:14][CH2:22][CH:19]3[CH2:18][CH2:17][N:16]([CH3:15])[CH2:21][CH2:20]3)[c:9]([O:12][CH3:13])[cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-e4a4eea406c0452f87451f8dbf549faf
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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