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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 941919Generated: November 1, 2026

Methanol → 5-Cyano-3-(2-fluoro-4-trimethylsilanyl-phenylamino)-pyrazine-2-carboxylic acid methyl ester

https://huagongshe.com/reaction/941919

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantCyanideHCID 5975—
ReactantDimethylformamideHCID 6228—
ReactantZinc(2+)HCID 32051—
Reactant5-Chloro-3-(2-fluoro-4-trimethylsilanyl-phenylamino)-pyrazine-2-carboxylic acid methyl esterHCID 59140180—
ReactantHCID 178420554HCID 178420554—
Product5-Cyano-3-(2-fluoro-4-trimethylsilanyl-phenylamino)-pyrazine-2-carboxylic acid methyl esterHCID 59140137—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-b0e1d9a22f024819a78a284823243e57
Source noteValidation data from https://doi.org/10.1039/C8SC04228D