Acetic Acid → Methyl 3-[(4-hydroxyphenyl)sulfonylamino]-2-(4-methylsulfonylpiperazin-1-yl)propanoate

HRID 942157Notes

Reaction equation

HRID 942157 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][c:12]([S:15](=[O:16])(=[O:17])[NH:18][CH2:19][CH:20]([C:21](=[O:22])[O:23][CH3:24])[N:25]2[CH2:26][CH2:27][N:28]([S:31](=[O:32])(=[O:33])[CH3:34])[CH2:29][CH2:30]2)[cH:13][cH:14]1.[CH3:35][CH2:36][OH:37].[CH3:44][C:45](=[O:46])[OH:47].[O:38]1[CH2:39][CH2:40][O:41][CH2:42][CH2:43]1>>[OH:8][c:9]1[cH:10][cH:11][c:12]([S:15](=[O:16])(=[O:17])[NH:18][CH2:19][CH:20]([C:21](=[O:22])[O:23][CH3:24])[N:25]2[CH2:26][CH2:27][N:28]([S:31](=[O:32])(=[O:33])[CH3:34])[CH2:29][CH2:30]2)[cH:13][cH:14]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 702EthanolHCID 312751,4-DioxaneHCID 123851454Methyl 2-(4-methylsulfonylpiperazin-1-yl)-3-[(4-phenylmethoxyphenyl)sulfonylamino]propanoate

Product 1

HCID 123687321Methyl 3-[(4-hydroxyphenyl)sulfonylamino]-2-(4-methylsulfonylpiperazin-1-yl)propanoate

Sources & evidence

ORD record
ord-13f5264035ad4f99b3a3419e2112d1ec
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…