Dichloromethane → 3-chloro-4-chloroacetyl-9,10-dihydro-4H-thieno[3,4-b][1,5]benzodiazepin-10-one
Reaction equation
[CH2:25]([Cl:26])[Cl:27].[Cl:6][CH2:7][C:8](=[O:9])[N:10]1[c:11]2[c:12]([cH:22][s:23][cH:24]2)[C:13](=[O:21])[NH:14][c:15]2[c:16]1[cH:17][cH:18][cH:19][cH:20]2.[S:1]([Cl:2])(=[O:3])([Cl:4])=[O:5]>>[Cl:4][c:24]1[c:11]2[c:12]([cH:22][s:23]1)[C:13](=[O:21])[NH:14][c:15]1[c:16]([cH:17][cH:18][cH:19][cH:20]1)[N:10]2[C:8]([CH2:7][Cl:6])=[O:9]Participants
4
Sources & evidence
- ORD record
- ord-738805b5de56483eb3f46f146afe37a5
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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