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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 942238Generated: October 31, 2026

Acetic Acid → 5-[5-(1-Azetidinylmethyl)-3-thienyl]-3-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-1H-indole-7-carboxamide

https://huagongshe.com/reaction/942238

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantDimethyl SulfoxideHCID 679—
ReactantMethanolHCID 887—
ReactantSodium ionHCID 923—
ReactantAzetidineHCID 10422—
ReactantCyano-borohydrideHCID 498716—
Reactant3-(1,1-Dioxidotetrahydro-2H-thiopyran-4-yl)-5-(5-formyl-3-thienyl)-1H-indole-7-carboxamideHCID 59332569—
Product5-[5-(1-Azetidinylmethyl)-3-thienyl]-3-(1,1-dioxidotetrahydro-2H-thiopyran-4-yl)-1H-indole-7-carboxamideHCID 59332779—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-999d900b42d44538801ffc0daf817bb9
Source noteValidation data from https://doi.org/10.1039/C8SC04228D