Potassium Cation → 1-[3,5-Dibromo-4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]phenyl]ethanone

HRID 942253Notes

Reaction equation

HRID 942253 reaction equation
[Br:23][CH2:24][CH2:25][CH2:26][O:27][c:28]1[c:29]([Br:38])[cH:30][c:31]([C:35]([CH3:36])=[O:37])[cH:32][c:33]1[Br:34].[CH3:39][C:40]#[N:41].[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]3)[n:7][o:8]2)[cH:15][cH:16]1.[K+:17].[K+:18].[O-:19][C:20]([O-:21])=[O:22]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:24][CH2:25][CH2:26][O:27][c:28]4[c:29]([Br:38])[cH:30][c:31]([C:35]([CH3:36])=[O:37])[cH:32][c:33]4[Br:34])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:15][cH:16]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 8494213-(4-Piperidyl)-6-fluoro-1,2-benzisoxazoleHCID 219601181-[4-(3-Bromopropoxy)-3,5-dibromophenyl]ethanone

Product 1

HCID 219600591-[3,5-Dibromo-4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]propoxy]phenyl]ethanone

Sources & evidence

ORD record
ord-2d8e0fde29e84d61a5d2dfbe8ea41778
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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