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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 942284Generated: October 26, 2026

1,2-Dimethoxyethane → 1-({5-[3,5-bis(Trifluoromethyl)phenyl]-1,2,4-thiadiazol-3-yl}methyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/942284

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantFluoride IonHCID 28179—
ReactantCesium cationHCID 104967—
Reactant3,5-Bis-trifluoromethylphenylboronic acidHCID 156265—
Reactant1-[(5-Chloro-1,2,4-thiadiazol-3-yl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67405013—
Product1-({5-[3,5-bis(Trifluoromethyl)phenyl]-1,2,4-thiadiazol-3-yl}methyl)-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 86620709—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-855f15eaa6194e00adf861ddc66494b4
Source noteValidation data from https://doi.org/10.1039/C8SC04228D