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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 942363Generated: October 31, 2026

Sodium ion → 4-[(4-Fluorophenyl)hydroxymethyl]-3-(hydroxymethyl)benzenecarbonitrile

https://huagongshe.com/reaction/942363

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantAcetonitrileHCID 6342—
ReactantTetrahydrofuranHCID 8028—
Reactant1-Bromo-4-fluorobenzeneHCID 9993—
ReactantBorohydrideHCID 28123—
ReactantLithium ionHCID 28486—
ReactantAluminum CationHCID 104727—
ReactantHydrideHCID 166653—
Reactant5-BromophthalideHCID 603144—
Reactant1,3-Dihydro-1-oxoisobenzofuran-5-carbonitrileHCID 821218—
ReactantMagnesiumHCID 5462224—
Product4-[(4-Fluorophenyl)hydroxymethyl]-3-(hydroxymethyl)benzenecarbonitrileHCID 9921362—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetValidation data from https://doi.org/10.1039/C8SC04228D
ORD IDord-e80d231544c14a7292bef7c34202fd1a
Source noteValidation data from https://doi.org/10.1039/C8SC04228D