HRID942446

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8028

Tetrahydrofuran

C4H8O

HCID11776

Triphenylphosphine

C18H15P

HCID592797

2-Chloro-4-hydroxybenzonitrile

C7H4ClNO

HCID22647631

1-{4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethan-1-ol

C13H12F3NOS

PRODUCTS

生成物

结构：Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(C)Oc1ccc(C#N)c(Cl)c1

HCID59556334

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f4ee98eac2c94f7f9d56282d3869987c
来源数据集: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D
来源说明: Validation data from https://doi.org/10.1039/C8SC04228D

反应 SMILES

[CH3:1][c:2]1[n:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)[s:5][c:6]1[CH:7]([CH3:8])[OH:9].[Cl:20][c:21]1[c:22]([C:23]#[N:24])[cH:25][cH:26][c:27]([OH:29])[cH:28]1.[O:49]1[CH2:50][CH2:51][CH2:52][CH2:53]1.[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1>>[CH3:1][c:2]1[n:3][c:4](-[c:10]2[cH:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)[s:5][c:6]1[CH:7]([CH3:8])[O:9][c:27]1[cH:26][cH:25][c:22]([C:23]#[N:24])[c:21]([Cl:20])[cH:28]1