1-[4-(2,2,2-Trifluoro-ethyl)-thiazol-2-yl]-piperazine → (2-Isopropoxy-5-methanesulfonyl-phenyl)-{4-[4-(2,2,2-trifluoro-ethyl)-thiazol-2-yl]-piperazin-1-yl}-methanone

HRID 942683Notes

Reaction equation

HRID 942683 reaction equation
[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[c:6]([C:7](=[O:8])[OH:9])[cH:10][c:11]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:12][cH:13]1.[F:18][C:19]([CH2:20][c:21]1[n:22][c:23]([N:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[s:24][cH:25]1)([F:32])[F:33]>>[CH:1]([CH3:2])([CH3:3])[O:4][c:5]1[c:6]([C:7](=[O:9])[N:29]2[CH2:28][CH2:27][N:26]([c:23]3[n:22][c:21]([CH2:20][C:19]([F:18])([F:32])[F:33])[cH:25][s:24]3)[CH2:31][CH2:30]2)[cH:10][c:11]([S:14](=[O:15])(=[O:16])[CH3:17])[cH:12][cH:13]1

Participants

3

Reactant 2

HCID 211001721-[4-(2,2,2-Trifluoro-ethyl)-thiazol-2-yl]-piperazineHCID 211002372-Isopropoxy-5-methylsulfonylbenzoic acid

Product 1

HCID 21100238(2-Isopropoxy-5-methanesulfonyl-phenyl)-{4-[4-(2,2,2-trifluoro-ethyl)-thiazol-2-yl]-piperazin-1-yl}-methanone

Sources & evidence

ORD record
ord-2fff4147ca4445deba9bb97f2e6fef83
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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