Dimethyl Sulfoxide → 4-(9-cyclopentyl-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-ylamino)-3-methoxy-N-(1-BOC-piperidin-4-yl)benzamide
Reaction equation
[CH3:45][S:46]([CH3:47])=[O:48].[CH:1]1([N:6]2[c:7]3[c:8]([cH:15][n:16][c:17]([NH:19][c:20]4[c:21]([O:29][CH3:30])[cH:22][c:23]([C:24](=[O:25])[OH:26])[cH:27][cH:28]4)[n:18]3)[N:9]([CH3:14])[C:10](=[O:13])[CH2:11][CH2:12]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[NH2:31][CH:32]1[CH2:33][CH2:34][N:35]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:36][CH2:37]1>>[CH:1]1([N:6]2[c:7]3[c:8]([cH:15][n:16][c:17]([NH:19][c:20]4[c:21]([O:29][CH3:30])[cH:22][c:23]([C:24](=[O:26])[NH:31][CH:32]5[CH2:33][CH2:34][N:35]([C:38](=[O:39])[O:40][C:41]([CH3:42])([CH3:43])[CH3:44])[CH2:36][CH2:37]5)[cH:27][cH:28]4)[n:18]3)[N:9]([CH3:14])[C:10](=[O:13])[CH2:11][CH2:12]2)[CH2:2][CH2:3][CH2:4][CH2:5]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-decc11f9005241d8bb394c4eebd14b79
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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