Methanol → 6-Amino-9-benzyl-2-(3-hydroxypropoxy)-8-methoxypurine

HRID 942691Notes

Reaction equation

HRID 942691 reaction equation
[CH3:24][OH:25].[CH3:26][O-:27].[CH3:29][OH:30].[NH2:1][c:2]1[c:3]2[n:4][c:5]([Br:23])[n:6]([CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[c:7]2[n:8][c:9]([O:11][CH2:12][CH2:13][CH2:14][OH:15])[n:10]1.[Na+:28]>>[NH2:1][c:2]1[c:3]2[n:4][c:5]([O:25][CH3:24])[n:6]([CH2:16][c:17]3[cH:18][cH:19][cH:20][cH:21][cH:22]3)[c:7]2[n:8][c:9]([O:11][CH2:12][CH2:13][CH2:14][OH:15])[n:10]1

Participants

5

Reactant 4

HCID 887Methanol2×HCID 923Sodium ionHCID 3826051MethoxideHCID 183327536-Amino-9-benzyl-8-bromo-2-(3-hydroxypropoxy)purine

Product 1

HCID 183327906-Amino-9-benzyl-2-(3-hydroxypropoxy)-8-methoxypurine

Sources & evidence

ORD record
ord-2241c623da754e8b8ec216dd1b1328c2
Source dataset
Validation data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…