Ethanol → 2-(2,5-Difluorophenyl)pyrrolidine

HRID 942798Notes

Reaction equation

[BH4-:1].[CH3:16][CH2:17][OH:18].[F:3][c:4]1[c:5]([C:11]2=[N:15][CH2:14][CH2:13][CH2:12]2)[cH:6][c:7]([F:10])[cH:8][cH:9]1.[Na+:2]>>[F:3][c:4]1[c:5]([CH:11]2[CH2:12][CH2:13][CH2:14][NH:15]2)[cH:6][c:7]([F:10])[cH:8][cH:9]1

Participants

Reactant 4

HCID 702Ethanol

HCID 923Sodium ion

HCID 28123Borohydride

HCID 583357265-(2,5-difluorophenyl)-3,4-dihydro-2H-pyrrole

Product 1

HCID 246978582-(2,5-Difluorophenyl)pyrrolidine

Sources & evidence

ORD record: ord-3590f50b9b8e40d1a02c6360c6be4479
Source dataset: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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