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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 94290Generated: October 30, 2026

1,2-Dichloroethane → 3-cyclohexyl-1-methyl-1-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea

https://huagongshe.com/reaction/94290

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantDimethyl SulfoxideHCID 679—
ReactantMethylamineHCID 6329—
ReactantCyclohexyl isocyanateHCID 18502—
Reactant2-bromo-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[2,3-b]pyrazineHCID 57516597—
ReactantMethyl-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-amineHCID 67385648—
Product3-cyclohexyl-1-methyl-1-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-ureaHCID 67385335—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-29630540d28d4099912c3f4eb8bd6539
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)