(Pyrimidin-5-yl)boronic acid → 8-Cyclopentyl-4-methyl-2-(methylamino)-6-(pyrimidin-5-yl)pyrido[2,3-d]pyrimidin-7(8H)-one
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([NH:11][CH3:12])[n:8][c:9]2[CH3:10])[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15].[n:21]1[cH:22][n:23][cH:24][c:25]([B:27]([OH:28])[OH:29])[cH:26]1>>[c:2]1(-[c:25]2[cH:24][n:23][cH:22][n:21][cH:26]2)[cH:3][c:4]2[c:5]([n:6][c:7]([NH:11][CH3:12])[n:8][c:9]2[CH3:10])[n:13]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20]2)[c:14]1=[O:15]Participants
3
Sources & evidence
- ORD record
- ord-ae7883904b884bbcaeab0d7a8d037f25
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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