Acetonitrile → 7-[3-[(Ethylamino)methyl]-1-pyrrolidinyl]-6,8-difluoro-1,4-dihydro-1-methylamino-4-oxo-3-quinolinecarboxylic acid
Reaction equation
[CH2:20]([CH3:21])[NH:22][CH2:23][CH:24]1[CH2:25][NH:26][CH2:27][CH2:28]1.[CH3:29][C:30]#[N:31].[F:1][c:2]1[cH:3][c:4]2[c:5](=[O:19])[c:6]([C:16](=[O:17])[OH:18])[cH:7][n:8]([NH:14][CH3:15])[c:9]2[c:10]([F:13])[c:11]1[F:12]>>[F:1][c:2]1[cH:3][c:4]2[c:5](=[O:19])[c:6]([C:16](=[O:17])[OH:18])[cH:7][n:8]([NH:14][CH3:15])[c:9]2[c:10]([F:13])[c:11]1[N:26]1[CH2:25][CH:24]([CH2:23][NH:22][CH2:20][CH3:21])[CH2:28][CH2:27]1Participants
4
Sources & evidence
- ORD record
- ord-e406a3137026422b89f0e4a732357558
- Source dataset
- Validation data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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